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Ingredients: Water, Glycerin, Propylene Glycol, Polyglycerin-10, 1,2-Hexanediol, Hydroxyacetophenone, Resveratrol, Carbomer, Triethanolamine, Panthenol, Hydrolyzed Collagen, Sodium Hyaluronate, Mannitol, Sodium DNA, Phenoxyethanol, Nicotinamide Adenine Dinucleotide, Disodium EDTA, Sodium Chloride, Ethylhexylglycerin, Leuconostoc/Radish Root Ferment Filtrate, Copper Tripeptide-1, Sh-Polypeptide-1
Clinical-level concentration serum with 0.08% NAD⁺ and 1000 ppm PDRN and GHK-CU to support visible firmness, renewal and skin resilience. Compatible with dermaroller, RF, microcurrent and ultrasound treatments.
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• Region 1: from €7 (2–3 business days)
• Region 2: from €9,9 (2–3 business days)
• Region 3: from €14,9 (3–7 business days)
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An intensive NAD⁺ + 1000 ppm PDRN serum formulated at professional-strength concentrations to support skin cellular energy, regeneration and structural firmness.
When skin begins to lose firmness, density and resilience, the issue is often deeper than surface dehydration. Aging starts at the cellular level — where energy production slows, regeneration weakens and structural proteins decline. This serum was created to target that level.
This serum is designed for results-focused routines — where active concentration and biological relevance matter.
NAD⁺ and 1000 ppm PDRN and Copper Tripeptide (GHK-CU) work together to support visible renewal, stronger-looking skin structure and improved resilience over time.
Backed by 18 years of aesthetic expertise, DermaGene® follows a concentration-driven approach — engineered for long-term skin quality, not temporary smoothing.
Nicotinamide Adenine Dinucleotide is a key cellular energy molecule involved in metabolic and regenerative processes. NAD⁺ levels decline with age. This formula supports skin vitality and renewal by focusing on cellular energy metabolism. NAD⁺ use in cosmetic formulations remains rare, especially at this concentration.
Potent antioxidant protection against environmental stressors.
Salmon-derived polynucleotide known for supporting skin regeneration, calming irritated tissue and improving overall skin quality. 1000 ppm represents a high-performance concentration with visible impact.
Supports skin structure integrity and elasticity.
European Aesthetic Expertise
This high-concentration formula is built around ingredients widely studied in dermatological and cosmetic science for their role in supporting visible skin renewal, firmness and structural integrity.
Nicotinamide Adenine Dinucleotide (NAD⁺) is a coenzyme naturally present in cells and associated in scientific literature with cellular energy metabolism. In topical cosmetic formulations, it is included to support skin vitality and overall appearance.
Sodium DNA (PDRN) is used in advanced skincare for its association with skin regeneration pathways and structural support in cosmetic applications.
Copper Tripeptide-1 and sh-Polypeptide-1 (EGF-related peptide) are peptide-based ingredients studied for their role in supporting skin firmness, visible renewal and improved texture when used in topical formulations.
Resveratrol is a well-documented antioxidant polyphenol known for helping protect the skin against oxidative stress.
Sodium hyaluronate, glycerin and polyglycerin-10 contribute multi-level hydration support, while panthenol and hydrolyzed collagen assist in maintaining skin comfort and surface conditioning.
Developed at clinical-level concentration standards, this formula is designed for advanced routines focused on long-term skin quality and visible structural support.
A central coenzyme in cellular energy metabolism, increasingly studied in skin-aging pathways and cellular vitality research.
Study: https://pubmed.ncbi.nlm.nih.gov/39513906/
Review (open access): https://pmc.ncbi.nlm.nih.gov/articles/PMC11544843/
Explored in dermatological research for its association with regeneration-related signaling and structural skin support mechanisms.
Review (open access): https://pmc.ncbi.nlm.nih.gov/articles/PMC5405115/
Study: https://pubmed.ncbi.nlm.nih.gov/37959659/
A well-documented copper-binding peptide studied for its role in extracellular matrix–related pathways and skin-supportive signaling.
Review: https://pubmed.ncbi.nlm.nih.gov/29986520/
Study (open access): https://pmc.ncbi.nlm.nih.gov/articles/PMC3016279/
EGF-related peptides are widely investigated in dermatological science for their relevance to skin renewal and tissue homeostasis research.
Dermatology review (open access): https://pmc.ncbi.nlm.nih.gov/articles/PMC10333026/
30+ age group: Early signs of aging, dullness, under-eye shadows, mild laxity.
40+ age group: Structural weakening, volume loss, visible firmness reduction.
Post-treatment recovery
Excellent after aesthetic procedures due to Copper Tripeptide strengthening and Panthenol soothing support.
Thinning, sagging or weakened skin
Most wrinkle serums focus on surface hydration. NAD⁺ and PDRN formulas target biological regenerative processes, not only superficial smoothing.
NAD⁺ is a cellular energy molecule involved in metabolism and regeneration. Levels decline with age.
1000 ppm equals 0.1% concentration. This is higher than many commercial PDRN serums. If ppm is not disclosed, the active level is often negligible.
Yes. Patch testing is recommended before first use.
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