DermaGene® STEP 3 BIO-RECODE™ NAD+ PDRN Bio-Collagen Weekly Reset Mask

DermaGene® STEP 3 BIO-RECODE™ NAD+ PDRN Bio-Collagen Weekly Reset Mask

One Night. One Mask. Your Weekly Skin Reset. Wake up to skin that looks like it has just had a professional facial. . BIO-RECODE™ is a long-wear hydrogel ritual with NAD+, salmon-derived PDRN, peptides and multi-layer hydration, created to help tired, dry-looking skin appear smoother, plumper, calmer and beautifully refreshed by...

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DermaGene® STEP 3 BIO-RECODE™ NAD+ PDRN Bio-Collagen Weekly Reset Mask

€ 7,00

Quantity:

DermaGene® STEP 3 BIO-RECODE™ NAD+ PDRN Bio-Collagen Weekly Reset Mask

€ 7,00

Featured in

Not Just Another Collagen Mask. Your Weekly Skin Reset.

There are days when hydration alone does not feel like enough.

When your skin looks tired, feels depleted or no longer has the smooth, rested appearance you want, BIO-RECODE™ offers a slower, more intensive kind of care.

This long-wear bio-collagen hydrogel mask combines NAD+, salmon-derived PDRN, structural peptides, multi-layer hyaluronic acid and barrier-supporting botanicals in one weekly home ritual.

Wear it for 4–5 hours or overnight. As the hydrogel gradually becomes transparent, your skin remains in prolonged contact with its concentrated essence—helping it look plumper, calmer, smoother and visibly refreshed.

One mask. One evening. A complete reset for tired-looking skin.

The Weekly Reset Your Skin Has Been Waiting For

Every day, the skin is exposed to environmental stress, changing temperatures, lack of sleep, active skincare and lifestyle-related fatigue. Over time, it may begin to appear duller, less comfortable and less resilient.

BIO-RECODE™ was created for the moment when your everyday routine needs something more.

Not a quick 15-minute mask. Not a temporary layer of moisture.

A weekly, professional-inspired ritual designed to support:

✓ A fresher, more rested appearance
✓ Long-lasting hydration and comfort
✓ Smoother, plumper-looking skin
✓ The appearance of firmness and elasticity
✓ A stronger, healthier-looking moisture barrier
✓ A more luminous and even-looking complexion

Salmon-Derived PDRN

PDRN is known from professional recovery-focused and aesthetic skincare routines. In BIO-RECODE™, salmon-derived Sodium DNA complements the mask’s soothing, conditioning and skin-quality-focused formula.

Structural Peptide Complex

A combination of Palmitoyl Pentapeptide-4, Acetyl Hexapeptide-8 and Palmitoyl Tetrapeptide-7 helps support smoother-looking texture, visible firmness and a more refined complexion.

NAD+

NAD+ is naturally associated with cellular energy processes. Within the BIO-RECODE™ formula, it forms part of a vitality-focused skincare complex created to help tired-looking skin appear fresher, more energised and renewed.

Multi-Layer Hyaluronic Acid

Multiple forms of hyaluronic acid help attract and retain moisture across different layers of the skin’s surface, supporting a plumper, more supple and comfortably hydrated appearance.

What Makes BIO-RECODE™ Different?

More than temporary hydration: BIO-RECODE™ brings together hydration, barrier-conscious care, peptides and vitality-focused ingredients in one coordinated weekly treatment.
Designed for extended wear: Unlike a traditional sheet mask, it may be worn for 4–5 hours or overnight, allowing the essence to remain in close contact with the skin for longer.
An advanced ingredient combination: The formula pairs NAD+ and salmon-derived PDRN with peptides, multiple forms of hyaluronic acid and comforting botanical extracts.
Created for visibly tired skin: Reach for it when your complexion appears dull, dry, stressed, less firm or simply in need of extra care.
Part of a complete skincare system: BIO-RECODE™ is STEP 3 of the DermaGene® Cellular Longevity Routine, complementing the daily serum and barrier-supporting cream.
A ritual you will look forward to: The gradually transparent hydrogel turns intensive skincare into a slower, more luxurious weekly moment.

The DermaGene® Cellular Longevity Routine

Three Steps. One Complete Skin-Renewal Ritual.
STEP 1 – NAD+ Radiant Longevity Serum

A lightweight daily serum with NAD+, 1000 ppm salmon-derived PDRN, resveratrol and copper peptides. Designed to support visible vitality, firmness and long-term skin quality.

STEP 2 – PDRN2000 Cellular Recovery Cream

A barrier-focused cream with 2000 ppm PDRN, ceramides, Centella asiatica, hyaluronic acid and panthenol. Created to restore comfort and support a stronger, more resilient-looking moisture barrier.

STEP 3 – BIO-RECODE™ Weekly Reset Mask

The intensive weekly step. A long-wear hydrogel mask combining NAD+, PDRN, peptides and barrier-supporting ingredients for visibly plumper, calmer and more rested-looking skin.

Together, the three steps create a coordinated longevity-focused routine built around daily vitality, barrier care and weekly intensive recovery.

Use with your device- Enhance results

BIO-RECODE™ is designed to complement microneedling, radiofrequency, IPL and laser-based skincare routines with an intensive, recovery-focused step. These technologies may temporarily leave the skin feeling dry, tight or more sensitive, making hydration, comfort and barrier-conscious care especially important between treatments.

Its long-wear hydrogel format keeps the skin in prolonged contact with PDRN, NAD+, peptides and soothing botanical ingredients, helping the complexion appear plumper, smoother, calmer and more refreshed.

How to Pair It with Your Routine

Between microneedling sessions: Use once the skin has calmed and is ready for regular cosmetic skincare. It supports hydration and comfort without introducing another intensive active step.
After radiofrequency treatments: Once the skin has returned to its normal temperature and shows no persistent irritation, BIO-RECODE™ can be used to restore moisture and support a smoother, more rested-looking complexion.
Between IPL or laser sessions: After the initial recovery period, the mask can help replenish hydration, support barrier comfort and maintain healthy-looking skin between appointments.
As an intensive hydration treatment: Use it when the skin looks dull, depleted or particularly dry, either as part of a professional hydration programme or as the final intensive step in your weekly routine.
For long-term at-home maintenance: Regular skincare between treatments helps maintain hydration, comfort and overall skin quality, making BIO-RECODE™ a valuable part of a consistent home ritual.

DERMAGENE®

Not inspired by clinics.
Developed within them.

Every technology we include was validated by aesthetic professionals and physicians — delivering complete home aesthetic protocols, not standalone devices.

AWARD-WINNING · 18 YEARS · 40,000+ DEVICES ACROSS EUROPE · CE CERTIFIED

RECOGNIZED BY ELLE · MARIE CLAIRE · JOY · GLAMOUR · FORBES

Scientific Background

BIO-RECODE™ combines a long-wear hydrogel format with NAD+, salmon-derived PDRN, Palmitoyl Pentapeptide-4, Acetyl Hexapeptide-8, Palmitoyl Tetrapeptide-7, multi-form hyaluronic acid, panthenol and Centella asiatica. These ingredients were selected to support prolonged hydration, skin comfort, barrier care and a smoother, more rested-looking complexion.

In a 12-week, double-blind, placebo-controlled split-face study involving 93 women aged 35–55, a moisturiser containing 3 ppm Palmitoyl Pentapeptide-4 produced significantly greater improvements in the appearance of fine lines and wrinkles than the control moisturiser.

Hydration and barrier-supporting ingredients also have relevant human data. In a randomized, assessor-blinded study of 20 women, a topical formula containing 1% hyaluronic acid, 5% glycerin and Centella asiatica increased measured skin hydration by 59% after 1 hour, 48% after 8 hours and 29% after 24 hours. After 24 hours, transepidermal water loss was also lower in the treated area than in the untreated control area.

Centella asiatica has also been studied separately in cosmetic formulations. In a four-week study involving 25 volunteers, creams and hydrogels containing 2.5% or 5% Centella asiatica extract improved stratum-corneum hydration and reduced transepidermal water loss, with the 5% formulations showing the strongest results.

Panthenol supports the barrier-comfort positioning of the formula. In a randomized, double-blind, placebo-controlled human study, seven days of topical dexpanthenol use significantly increased stratum-corneum hydration and reduced transepidermal water loss compared with the vehicle control.

Research into PDRN is promising, particularly in medical and aesthetic recovery applications, but most robust clinical evidence currently relates to injected or professional use rather than topical hydrogel masks. Topical NAD+ is likewise an emerging field, and its cosmetic performance depends strongly on formulation stability and delivery. For this reason, BIO-RECODE™ positions these ingredients as part of an advanced, vitality- and recovery-inspired skincare formula rather than claiming that the finished mask reproduces medical treatment outcomes.

Scientific Background & References

Milani, Massimo, and Antonella Sparavigna. “The 24-Hour Skin Hydration and Barrier Function Effects of a Hyaluronic 1%, Glycerin 5%, and Centella Asiatica Stem Cells Extract Moisturizing Fluid: An Intra-Subject, Randomized, Assessor-Blinded Study.” Clinical, Cosmetic and Investigational Dermatology, vol. 10, 2017, pp. 311–315. doi:10.2147/CCID.S144180.

Gehring, W., and M. Gloor. “Effect of Topically Applied Dexpanthenol on Epidermal Barrier Function and Stratum Corneum Hydration: Results of a Human In Vivo Study.” Arzneimittelforschung, vol. 50, no. 7, 2000, pp. 659–663. doi:10.1055/s-0031-1300268.

Lupo, Mary P., and André F. Cole. “Topical Palmitoyl Pentapeptide Provides Improvement in Photoaged Human Facial Skin.” International Journal of Cosmetic Science, vol. 27, no. 3, 2005, pp. 155–160. doi:10.1111/j.1467-2494.2005.00261.x.

Ratz-Łyko, Anna, et al. “Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella Asiatica Extract.” Indian Journal of Pharmaceutical Sciences, vol. 78, no. 1, 2016, pp. 27–33. doi:10.4103/0250-474X.180247.

Biro, Kathrin, et al. “Efficacy of Dexpanthenol in Skin Protection Against Irritation: A Double-Blind, Placebo-Controlled Study.” Contact Dermatitis, vol. 49, no. 2, 2003, pp. 80–84. doi:10.1111/j.0105-1873.2003.00184.x.

Stettler, Holger, et al. “A New Topical Panthenol-Containing Emollient: Results from Two Randomized Controlled Studies Assessing Its Skin Moisturization and Barrier Restoration Potential, and the Effect on Skin Microflora.” Journal of Dermatological Treatment, vol. 28, no. 2, 2017, pp. 173–180. doi:10.1080/09546634.2016.1214235

PDRN: The Next Generation of Skin Recovery or Just Another Trend?

Feature	PopularBIO-RECODE™ Weekly Reset Mask	Typical Bio-Collagen Hydrogel Mask	Traditional Sheet Mask
Primary focus	✦ Weekly recovery, barrier care, hydration and visible firmness	✓ Hydration and glow	✓ Quick hydration
PDRN	✦ Salmon-derived PDRN	Varies	Rarely included
NAD+	✦ Included	Rarely included	Rarely included
Peptide complex	✦ Three structural and expression-line-focused peptides	Varies	Limited
Hyaluronic acid	✦ Multi-layer hydration complex	✓ Usually included	✓ Often included
Barrier-supporting botanicals	✦ Centella, liquorice, green tea, chamomile and Polygonum cuspidatum	Varies	Varies
Recommended wear time	✦ 4–5 hours or overnight	3–4 hours or overnight	15–20 minutes
Changes in appearance during use	✦ Gradually becomes thinner and transparent	✓ Often transparent	✗ Remains a fabric sheet
Role in the routine	✦ Weekly Skin Reset Protocol	Hydrating mask	Occasional skincare step

✦ = exclusive · ✓ = yes · ✗ = no

FAQs

Yes, but it was created to offer more than a conventional collagen-mask experience. Alongside the bio-collagen hydrogel, the formula contains NAD+, salmon-derived PDRN, peptides, multiple forms of hyaluronic acid and barrier-supporting botanical extracts.

Wear it for at least 4–5 hours, or leave it on overnight. The hydrogel gradually becomes thinner and more transparent during use. Complete transparency is not required and can vary between users.

BIO-RECODE™ is designed as a once-weekly intensive ritual. It may also be used before a special event, after travelling or whenever the skin looks particularly tired and dehydrated.

Yes. Apply a thin layer of a lightweight, water-based serum and allow it to absorb before positioning the mask. Avoid applying a thick cream or facial oil underneath, as this may reduce adhesion.

Yes. BIO-RECODE™ fits naturally into a professional-inspired skincare routine and may be used between aesthetic treatments to support hydration, skin comfort and barrier care. Following an intensive professional procedure, simply wait until your practitioner advises that your regular skincare routine can be resumed before applying the mask.

DermaGene® STEP 3 BIO-RECODE™ NAD+ PDRN Bio-Collagen Weekly Reset Mask

Frequently Purchased Together

DermaGene® STEP 3 BIO-RECODE™ NAD+ PDRN Bio-Collagen Weekly Reset Mask

DermaGene® STEP 3 BIO-RECODE™ NAD+ PDRN Bio-Collagen Weekly Reset Mask

Featured in

Not Just Another Collagen Mask. Your Weekly Skin Reset.

The Weekly Reset Your Skin Has Been Waiting For