DermaGene® Clinical Longevity 3-Step Skin Renewal System – NAD+ Serum, PDRN Recovery Cream & Bio-Collagen Weekly Reset Mask

DermaGene® Clinical Longevity 3-Step Skin Renewal System – NAD+ Serum, PDRN Recovery Cream & Bio-Collagen Weekly Reset Mask

Longevity skincare for visibly revitalised skin. Powered by NAD⁺, PDRN and Bio-Collagen, this advanced three-step ritual helps restore the look of calm, hydrated and resilient skin—revealing a complexion that appears smoother, plumper and naturally radiant. 800 ppm NAD⁺ · 3000 ppm PDRN · Bio-Collagen Weekly Reset

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DermaGene® Clinical Longevity 3-Step Skin Renewal System – NAD+ Serum, PDRN Recovery Cream & Bio-Collagen Weekly Reset Mask

~~€ 150,00~~ € 132,00

Menge:

DermaGene® Clinical Longevity 3-Step Skin Renewal System – NAD+ Serum, PDRN Recovery Cream & Bio-Collagen Weekly Reset Mask

~~€ 150,00~~ € 132,00

Featured in

A 3-step NAD+ and PDRN ritual for skin that looks stronger, smoother and more alive.

The DermaGene® Clinical Longevity System pairs a concentrated serum, barrier-supporting cream and weekly bio-collagen mask to bring tired, dehydrated or less resilient skin back to a calmer, plumper-looking state. Powered by NAD+, PDRN, copper peptide, resveratrol, ceramides and hyaluronic acid, each step works in rhythm with the next — daily support, weekly reset, visibly healthier-looking skin.

Who Is This Routine For?

Designed for skin beginning to show signs of stress, ageing or reduced resilience.

It is especially suited to:

30+ skin experiencing early fine lines, dullness, tired-looking eyes or a first loss of firmness.

40+ skin that appears drier, thinner, less elastic or affected by visible volume loss.

Skin used alongside beauty devices, including RF, microcurrent, EMS, LED or ultrasound routines, when extra comfort and barrier support are needed.

Sensitive or weakened skin barriers prone to tightness, redness, irritation or slower recovery.

Your skin may need more than hydration if you notice persistent tightness after cleansing, increased sensitivity, ongoing dryness, dull or uneven tone, or a complexion that seems to recover more slowly.

When several of these signs appear together, the skin may benefit from a more complete routine focused on barrier support, soothing hydration and visible skin resilience.

Why Choose This Routine?

Because it is designed as a complete routine: The serum, cream and weekly mask are made to follow one another naturally. Each step supports a different need, so the routine feels considered, simple and easy to stay consistent with.
Because the active ingredients are at the heart of every step: With 800 ppm NAD⁺, 3000 ppm PDRN across the routine, copper peptide, resveratrol, ceramides, panthenol and hyaluronic acid, the system brings together some of the most exciting ingredients in modern longevity skincare.
Because tired skin often needs more than hydration: This routine is especially suited to skin that looks dull, feels tight, appears less firm or becomes more sensitive and slower to recover.
Because daily care and weekly reset work better together: The serum and cream support the skin every day, while the BIO-RECODE™ mask adds a more intensive weekly step for a smoother, plumper and more refreshed-looking complexion.
Because barrier support is built into the routine: Ceramides, cholesterol, phytosphingosine and panthenol help the skin feel calmer, softer and more comfortable, especially when it is dry, stressed or easily irritated.
Because it pairs beautifully with beauty-device treatments: The routine is an ideal complement to RF, microcurrent, EMS, LED, ultrasound and other technology-led treatments, when the skin benefits from extra comfort, hydration and barrier support.
Because it supports the skin as a whole: Rather than focusing on just one concern, it helps address dullness, dehydration, uneven texture, loss of firmness and reduced resilience in one balanced routine.

Weekly Reset: 4–6 Hour Hydrogel Bio-Infusion

A once-weekly bio-collagen hydrogel treatment designed to stay in close contact with the skin for 4–6 hours. As the mask gradually turns transparent, it delivers NAD⁺, PDRN, peptides, hyaluronic acid, collagen and barrier-supporting ingredients.

The result: skin that looks plumper, calmer, deeply hydrated and more rested — especially when it feels tired, dehydrated, sensitive or in need of extra support after beauty-device treatments.

Use with your device- Enhance results

After RF, microcurrent, EMS, LED, ultrasound, HIFU or other technology-led treatments, skin often needs more than hydration alone. It benefits from a calm, replenishing environment that supports comfort, barrier strength and recovery.

The DermaGene® Clinical Longevity System was created with this in mind. Its three-step routine helps:

soothe skin after intensive treatments
support the skin’s natural recovery process
reinforce the moisture barrier
reduce feelings of tightness and discomfort
restore softness and hydration
maintain a fresh, luminous post-treatment appearance
leave skin looking plumper, smoother and more rested

How to Pair It with Your Routine

Daily Ritual

After cleansing, apply STEP 1 NAD+ Radiant Longevity Serum to the face and neck. Follow with STEP 2 PDRN 2000 Cellular Recovery Cream to seal in hydration and complete the routine.

Weekly Reset

Once a week, use STEP 3 BIO-RECODE™ NAD+ PDRN Bio-Collagen Mask as an intensive 4–5 hour treatment or as part of your overnight routine.

Cleanse the skin thoroughly.
Apply STEP 1 NAD+ Radiant Longevity Serum.
Place the BIO-RECODE™ mask onto the skin.
Leave on for at least 4–5 hours or overnight.
Once the bio-collagen hydrogel becomes gradually translucent, remove the mask.
Gently massage the remaining essence into the skin.
Finish with STEP 2 PDRN 2000 Cellular Recovery Cream.

DERMAGENE®

Not inspired by clinics.
Developed within them.

Every technology we include was validated by aesthetic professionals and physicians — delivering complete home aesthetic protocols, not standalone devices.

AWARD-WINNING · 18 YEARS · 40,000+ DEVICES ACROSS EUROPE · CE CERTIFIED

RECOGNIZED BY ELLE · MARIE CLAIRE · JOY · GLAMOUR · FORBES

Scientific Background

Longevity Support: NAD⁺ for a More Energised-Looking Complexion

At the heart of the routine is NAD⁺, one of the most exciting ingredients in modern longevity skincare. The serum contains 0.08% / 800 ppm NAD⁺, while the weekly hydrogel mask adds further support to the ritual.

This helps tired, dull or stressed-looking skin appear fresher, more rested and visibly more alive.

3000 ppm PDRN Across the Routine

The system delivers 1000 ppm PDRN in the serum and 2000 ppm PDRN in the cream.

The serum provides lightweight daily support, while the cream offers a richer layer of comfort and barrier care. Together, they help the skin feel more hydrated, plump, supple and resilient, especially during periods of stress or after beauty treatments.

Antioxidant Support: Resveratrol + Botanical Extracts

The formula combines 0.5% resveratrol with antioxidant and soothing botanical extracts, including green tea, liquorice, Polygonum Cuspidatum, Scutellaria Baicalensis, chamomile and rosemary.

This blend helps support a clearer, brighter and more even-looking complexion, with the fresh, well-rested appearance of skin in balance.

Peptide Complex for Smoother, Firmer-Looking Skin

A premium peptide system, including Copper Tripeptide-1, Palmitoyl Pentapeptide-4, Acetyl Hexapeptide-8 and Palmitoyl Tetrapeptide-7, supports smoother texture, elasticity and a more refined appearance.

The aim is not an artificial tightening effect, but skin that looks healthier, firmer and more supported over time.

Barrier Rebuild: Ceramides, Panthenol + Lipid Support

The routine also focuses on the foundation of healthy-looking skin: a strong, balanced barrier.

A blend of Ceramide NP, AP and EOP, phytosphingosine, cholesterol, panthenol and barrier lipids helps reduce feelings of tightness, support moisture retention and improve skin comfort.

The result is skin that feels softer, calmer and more resilient, especially when it is dry, sensitive or more reactive after treatments.

Scientific Background & References

Koo, Youngmi, and Yeoheung Yun. “Effects of Polydeoxyribonucleotides (PDRN) on Wound Healing: Electric Cell-Substrate Impedance Sensing (ECIS).” Materials Science and Engineering: C, vol. 69, 2016, pp. 554–560. https://doi.org/10.1016/j.msec.2016.06.094.

Robinson, L. R., et al. “Topical Palmitoyl Pentapeptide Provides Improvement in Photoaged Human Facial Skin.” International Journal of Cosmetic Science, vol. 27, no. 3, 2005, pp. 155–160. https://doi.org/10.1111/j.1467-2494.2005.00261.x.

Miller, Timothy R., et al. “Effects of Topical Copper Tripeptide Complex on CO2 Laser-Resurfaced Skin.” Archives of Facial Plastic Surgery, vol. 8, no. 4, 2006, pp. 252–259. https://doi.org/10.1001/archfaci.8.4.252. Man,

Mao-Qiang, et al. “Optimization of Physiological Lipid Mixtures for Barrier Repair.” Journal of Investigative Dermatology, vol. 106, no. 5, 1996, pp. 1096–1101. https://doi.org/10.1111/1523-1747.ep12340135

DermaGene® Clinical Longevity 3-Step Skin Renewal System – NAD+ Serum, PDRN Recovery Cream & Bio-Collagen Weekly Reset Mask

Frequently Purchased Together

DermaGene® Clinical Longevity 3-Step Skin Renewal System – NAD+ Serum, PDRN Recovery Cream & Bio-Collagen Weekly Reset Mask

DermaGene® Clinical Longevity 3-Step Skin Renewal System – NAD+ Serum, PDRN Recovery Cream & Bio-Collagen Weekly Reset Mask

Featured in

A 3-step NAD+ and PDRN ritual for skin that looks stronger, smoother and more alive.

Who Is This Routine For?

Why Choose This Routine?

Weekly Reset: 4–6 Hour Hydrogel Bio-Infusion